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| 2024 | • |
Improvement of Asymmetric Reactions via Remote Electronic Tuning of N-Heterocyclic Carbene Catalysts |
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Total Synthesis of 1,4a-di-epi-ent-Pancratistatin, Exemplifying a Stereodivergent Approach to Pancratistatin Isomers |
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遠隔位電子チューニングによるN-複素環式カルベン触媒の高性能化 |
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5-exo-Selective Asymmetric Bromolactonization of Stilbenecarboxylic Acids Catalyzed by Phenol-bearing Chiral Thiourea. |
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| 2023 | • |
Evaluation of Quantum Chemistry Calculation Methods for Conformational Analysis of Organic Molecules Using A-Value Estimation as a Benchmark Test. |
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Remote Electronic Tuning of Chiral N-Heterocyclic Carbenes. |
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Remote Electronic Effect of Chiral N-Heterocyclic Carbene Catalyst on an Asymmetric Benzoin Reaction. |
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Remote Electronic Effect on the N-Heterocyclic Carbene-catalyzed Asymmetric Intramolecular Stetter Reaction and Structural Revision of Products.
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Preparation of N-2-Nitrophenylsulfenyl Imino Peptides and Their Catalyst-Controlled Diastereoselective Indolylation. 
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| 2022 | • |
Kinetic Resolution of α-Hydroxyamide via N-Heterocyclic Carbene-Catalyzed Acylation. |
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Enhanced Molecular Recognition through SubstrateAdditive Complex Formation in N-Heterocyclic-Carbene-Catalyzed Kinetic Resolution of α-Hydroxythioamides. |
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| 2021 | • |
The Rationale for Stereoinduction in Conjugate Addition to Alkylidenemalonates Bearing a Menthol-derived Chiral Auxiliary.
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Mechanistic Support for Intramolecular Migrative Cyclization of Propargyl Sulfones Provided by Catalytic Asymmetric Induction with a Chiral Counter Cation Strategy.
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Synthesis of Non-canonical Amino Acids and Peptide Containing Them for Establishment of the Template for Drug Discovery
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| 2020 | • |
Helical Nanographenes Embedded with Contiguous Azulene Units.
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| • | Cloning and Expression of a Perilla frutescens Cytochrome P450 Enzyme Catalyzing the Hydroxylation of Phenylpropenes. Baba, M.; Yamada, K.; Ito, M. Plants 2020, 9 (5), 577. |
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| • | Development of a 1,3a,6a-triazapentalene derivative as a compact and thiol-specific fluorescent labeling reagent. Nakayama, A.; Otani, A.; Inokuma, T.; Tsuji D.; Mukaiyama, H.; Nakayama, A.; Itoh, K.; Otaka, A.; Namba, K. Commun. Chem. 2020, 3, 6. |
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| 2019 | • |
Asymmetric Synthesis of α-Amino Phosphonic Acids Using Stable Imino Phosphonate as a Universal Precursor.
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Total Syntheses of Allelopathic 4-Oxyprotoilludanes, Melleolides and Echinocidins.
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Synthesis of Functionalized Medium-Sized trans-Cycloalkenes by 4π Electrocyclic Ring Opening–Alkylation Cascade.
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Rapid Assembly of Protoilludane Skeleton through Tandem Catalysis: Total Synthesis of Paesslerin A and Its Structural Revision.
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Asymmetric Formal Synthesis of (+)-Catharanthine via Desymmetrization of Isoquinuclidine.
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Optical Resolution via Catalytic Generation of Chiral Auxiliary.
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| 2018 | • | ペプチドへの直接的不斉反応を基盤とした非天然アミノ酸含有ペプチドの新規効率的不斉合成法開発. 猪熊 翼 Yakugaku Zasshi 2018 , 138 (11), 1371–1379. |
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Aminolithiation–Arylation Consecutive Cyclization of N-(2-Fluorophenyl)methyl-aminoalkylstyryls Giving Aryl-substituted Pyrido[1,2-b]isoquinoline.
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A Recyclable Hydrophobic Anchor-Tagged Asymmetric Amino Thiourea Catalyst.
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Direct Enantioselective Indolylation of Peptidyl Imine for the Synthesis of Indolyl Glycine-Containing Peptides.
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| • | 薬学における生命指向型化学(実用的ケミカルバイオテクノロジーの開発を目指して). 猪熊 翼、佐藤 伸一, Yakugaku Zasshi 2018, 138 (1), 37–38. |
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| 2017 | • | A Convenient Method for Preparation of α-Imino Carboxylic Acid Derivatives and Application to the Asymmetric Synthesis of Unnatural α-Amino Acid Derivative. Tsubasa Inokuma, Takahisa Jichu, Kodai Nishida, Akira Shigenaga, and Akira Otaka, Chem. Pharm. Bull. 2017, 65 (6), 573–581. Highlighted paper selected by Editor-in-Chief |
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Synthesis of Multi-Substituted Cyclobutenes: Cyclic Strategy for [2+2] Cycloadditon of Ketene Silyl Acetals with Propiolates.
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Synthesis of π-Extended Fluoranthenes via a KHMDS-promoted Anionic-Radical Reaction Cascade.
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Synthesis and Biological Evaluation of Steroidal Derivatives Bearing a Small Ring as Vitamin D Receptor Agonists.
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Site-selective Benzoin-type Cyclization of Unsymmetrical Dialdoses Catalyzed by N-Heterocyclic Carbenes for Divergent Cyclitol Synthesis.
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Phosphine-Promoted Migrative Cyclization of Sulfonylalkynol and Sulfonylalkynamide for the Synthesis of Oxa- and Azacycles.
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| 2016 | • |
Use of a Catalytic Chiral Leaving Group for Asymmetric Substitutions at sp3-Hybridized Carbon Atoms: Kinetic Resolution of β-Amino Alcohols byp-Methoxybenzylation.
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Desymmetrization of Acid Anhydride with Asymmetric Esterification Catalyzed by Chiral Phosphoric Acid.
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Striking Difference between Succinimidomethyl and Phthalimidomethyl Radicals in Conjugate Addition to Alkylidenemalonate Initiated by Dimethylzinc.
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Oxa- and Azacycle-formation via Migrative Cyclization of Sulfonylalkynol and Sulfonylalkynamide with N-Heterocyclic Carbene.
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For those before 2016, see the link.
